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You are Here: LUHS > CHVM > Our Services > Heart Transplantation > Transplant Process Last Reviewed: Sept. 27, 2006

Transplant Process

Heart transplantation is the removal of a diseased heart and its replacement with a healthy human heart. The immediate goal of heart transplantation is restoring an individual’s physical health. The ultimate goal is to enable patients to enjoy an improved quality of life and to carry on with their family life, careers and hobbies.

Initial Interview
The steps toward a heart transplant begin when you, your physician or nurse contacts Loyola University Health System's (Loyola) Heart Transplant Program for a phone interview with a transplant nurse coordinator. During this interview process we will ask for your past and current medical conditions to determine if your condition warrants further evaluation for transplantation. This phone conversation may take 15-20 minutes to gather all of the information needed.

If indicated, an appointment will be scheduled for our Heart Transplant Clinic located in the Center for Heart & Vascular Medicine in Maywood, Ill. During this first appointment, you will meet one of our heart transplant cardiologists. For this appointment, we require a written medical summary from your physician, copies of past chest X-rays, past operative reports, cardiac catheterization films, blood tests and any other heart test results. If you and the transplant team decide to pursue a transplant evaluation, we will begin scheduling further testing.

 

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Work-Up
Although you have been told that you need a heart transplant to improve your condition, a final decision cannot be made until extensive testing is done. Tests to evaluate the condition of your heart, lungs, kidneys, immune system and nutrition may discover that:

  • continued medical treatment would improve your condition
  • a surgical procedure other than a transplant would be helpful
  • a condition exists that you are unaware of that would make transplantation unsuccessful

Your tests will be scheduled by the transplant team, and most tests can be done as an outpatient. Detailed instructions for each test will be given to you when they are scheduled. The evaluation includes multiple blood samples, pulmonary function tests, cardiac diagnostic testing, carotid and lower extremity arterial Doppler, CT scan of chest abdomen and pelvis and bone scan. When any of these test results are abnormal, further testing will be necessary.

Making the Decision
After your tests are completed, the doctors will review the results and propose the best treatment for you. If transplant is recommended, the risks and benefits of transplantation will be discussed with you and your family.

Waiting
Once the decision has been made that you are an eligible transplant candidate, your name will be placed on the national waiting list managed by the United Network for Organ Sharing. Waiting time for a suitable donor can be weeks or as long as two years. Many factors influence the actual waiting time, so it is difficult to predict just how long you will wait for a transplant. The matching of a donor heart is based on the following factors:

  • blood type of both the donor and recipient
  • height and weight of both the donor and recipient
  • waiting time of the potential recipient
  • medical condition of the potential recipient

You will receive a pager (free of charge) to keep you in touch with the Loyola team at all times. Special travel arrangements may need to be made if you live a great distance from Loyola University Medical Center.

Monthly education classes are available for the transplant candidate and their family to learn about the transplant process and life after transplant.

Mechanical Support
Mechanical support may be needed to improve circulation and improve a patient’s health while awaiting a transplant. Loyola is among a handful of medical centers in the country approved to use the latest mechanical heart pumps to serve as a bridge to transplantation.

When the heart could benefit from a small amount of pumping support, an intra-aortic balloon pump (IABP) may be used. The physician inserts the IABP into an artery in the patient’s groin and feeds it through the artery until it sits in the thoracic aorta and serves to lessen the work load of the heart by inflating and deflating in time with the heart’s contraction.

Some patients may require more assistance. A left ventricular assist device called the HeartMate may be used.The HeartMate is surgically implanted in the upper quadrant of the patient’s abdomen and takes over the work of the heart’s left ventricle. A driveline is connected through an opening in the patient’s abdomen to a battery pack. Loyolawas one of 16 medical centers to begin investigating the HeartMate in 1992, and in 1996 Loyola began testing a more advanced version of the device called the vented electric HeartMate. 

For patients whose heart has failed so drastically that they cannot be supported any other way, the total artificial heart provides the ultimate level of support. The patient’s own heart is removed and replaced with the mechanical heart. The heart is pumped by compressed air through tubes that exit the patient’s abdomen and connect to a computerized drive console.

  • From Jan. 1, 1988, to Aug. 31, 1990, Loyola implanted 19 Jarvik-7 total artificial hearts, and 17 of those patients were subsequently transplanted with donor hearts.
  • From July 1, 1994, to June 1, 2000, Loyola implanted the CardioWest total artificial heart in 16 patients, and 12 of those subsequently received donor hearts.
  • From Oct. 31, 1994 to April 2, 2002, Loyola implanted the CardioWest total artificial heart in 19 patients, and 14 of those subsequently received donor hearts

Transplantation
When the Loyola Heart Transplant Team is notified of an available organ, information about the medical condition and health history of the donor organ are obtained. The surgeon and transplant cardiologist will decide if the donor heart is healthy. The procurement team (surgeon & nurse) will travel to the donor hospital. If the donor is deemed unsuitable for transplant, the surgery is cancelled and you will continue to wait for a suitable organ.

The operation is performed by the heart transplant surgeon and the surgical team. Surgery will take approximately four to six hours.

Post-Operative Recovery
After surgery you will recover in the Surgical Intensive Care Unit. You will be on the breathing machine (ventilator) until you are able to breathe on your own. You will be transferred to the Heart Transplant Unit once you are medically stable.

Long-Term Discharge
By the third or fourth day after transplant, patients usually can walk and begin regaining their strength. Some patients can go home by the seventh or eighth day and continue independent exercises at home. Some may need home visits from a physical therapist to get back in condition. Patients who have spent a long time in the hospital and whose muscles are exceptionally weak may need a longer rehabilitation period. Those patients may need a short stay at a rehabilitation facility.

Long-Term Management of Heart Transplantation
You and the transplant team will work closely together to manage your long term health. Now that you have received your new heart, you will be responsible for lifetime management of your diet, lifestyle, medical follow-up appointments and testing and medications. Some activities must be done daily such as taking your blood pressure, weight and temperature to ensure your optimal health after transplantation.

Before you are discharged from the hospital, you and your family will receive instructions about your care at home for life. After discharge from the hospital, you will be seen by our transplant team weekly for two months, and then every other week during the next two months. Due to the frequency of these visits, you must reside in the Chicagoland area after discharge from the hospital. After returning to home, we will continue to manage your heart transplant care, and you will need to return to Loyola University Medical Center at least once a month for heart biopsies and physician appointments during the first year after heart transplantation.

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