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Jian-Zhong Qin, MD, PhD
 

  • Qin JZ, Xin H, Satailo LA, Denning MF, Nickoloff BJ. Enhanced killing of melanoma cells by simultaneously
    targeting Mcl-1 and NOXA. Cancer Res. 2006 Oct 1; 66(19): 9636- 45
  • Qin JZ , Ziffra J, Stennett L, Bodner B, Bennett F, Pollock PM, Trent JM, Hendrix M, Rizzo P, Miele L, Nickoloff BJ. Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma Cells. Cancer Res 2005 July 65(14): 6282-93
  • Qin JZ, Stennett L, Bacon P, Bodner B, Hendrix MJ, Seftor RE, Seftor EA, Margaryan NV, Pollock PM, Curtis A, Trent JM, Bennett F, Miele L, Nickoloff BJ. p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas. Mol Cancer Ther. 2004 Aug; 3(8):895-902.
  • Qin JZ, Bacon P, Panella J, Sitailo LA, Denning MF, Nickoloff BJ. Low-dose UV-radiation sensitizes keratinocytes to TRAIL-induced apoptosis. J Cell Physiol. 2004 Jul;200(1):155-66.
  • Qin JZ, Bacon PE, Chaturvedi V, Bonish B, Nickoloff BJ. Pathways involved in proliferating, senescencet and immortalized keratinocyte cell death mediated by two different Trail preparations. Exp Dermatol. 2002 Dec; 11(6):573-83
  • Qin JZ, Chaturvedi V, Denning MF, Choubey D, Nickoloff BJ. Regulation of apoptosis by P53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes. Oncogene. 2002 May; 21(19): 2991-3002
  • Qin JZ, Bacon P, Chaturvedi V, Nickoloff BJ. Role of NF-˙B in apoptotic response of keratinocytes mediated by interferon-˙, tumor necrosis factor-˙ and tumor –necrosis-factor-related apoptosis-inducing ligand. J Invest Dermatol. 2001 Oct; 117(4): 898-907
  • Qin JZ, Zhang CL, Kamarsshev J, Dummer R, Burg G, Dobbeling U. IL-7 and IL-15 regulate the expression of bcl-2 and c-myb genes in cutaneous T cell lymphoma (CTCL) cells. Blood. 2001 Nov; 98(9): 2778- 83
  • Qin JZ, Kamarashev J, Zhang CL, Dummer R, Burg G, Dobelling U. Constitutive and IL-7 and IL-15 stimulated DNA-binding of STAT and novel factors in cutaneous T cell lymphoma (CTCL) cells. J Invest Dermatol. 2001 Sep; 117(3): 583- 9
  • Qin JZ, Chaturvedi V, Bonish B, Nickoloff BJ. Avoiding premature apoptosis of normal epidermal cells. (Letter) Nature Medicine. 2001 Apr; 7(4): 385-386
  • Qin JZ, Chaturvedi V, Denning MF, Choubey D, Diaz MO, Nickoloff BJ. Role of NF-kappa B in the apoptotic-resistant phenotype of keratinocytes. J Biol Chem. 1999 Dec; 274(53): 37957-64
  • Qin JZ, Dummer R, Burg G, Dobbeling U. Constitutive and interleukin-7/interleukin-15 stimulated DNA binding of Myc, Jun, and novel Myc-like proteins in cutaneous T-cell lymphoma cells. Blood. 1999 Jan; 93(1): 260-7

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 Last reviewed: Nov. 15, 2007