Robinson JK, Nickoloff BJ: Digital epiluminsecence microscopy monitoring of high-risk patients. Arch Dermatol 140: 49-56, 2004.

Qin J-Z, Bacon P, Panella J, Sitailo L, Denning MF, Nickoloff BJ: Low dose UV-irradiation sensitizes keratinocytes to TRAIL induced apoptosis by reducing decoy receptors J Cell Physiol, 2004; 200: 155-66.

Chaturvedi V, Qin J-Z, Stennett L, Choubey D, Nickoloff BJ: Resistance to UV-induced apoptosis in human keratinocytes during accelerated senescence is associated with functional inactivation of p53. J Cell Physiol, 2004; 198: 100-109.

LePoole IC, Wankowicz-Kalinska A, Van den Winjngaard RMJGJ, Nickoloff BJ, Das PK. Autoimmune depigmentation in vitiligo. J Invest Dermatol Symp Proc, 2004; 9: 68-72.

Boyman O, Hefti HP, Suter M, Nickoloff BJ, Nestle FO: Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-. J Exp Med, 2004; 199: 731-736.

Song LL, Weijzen S, Qin J-Z, Nickoloff BJ, Kast WM, Miele L: Notch-1 regulates cell death independently of differentiation in murine erythroleukemia cells through multiple apoptosis and cell cycle pathways. J Cell Physiol, 2004; 99: 1-16.

Gerbitz A, Nickoloff BJ, Olkiewitz K, Willmarth NE, Hildebrandt G, Kobzik L, Eissner G, Holler E, Ferrara JLM, Cooke KR: A role for TNF- mediated endothelial apoptosis in the development of experimental idiopathic pneumonia syndrome. Transplantation, 2004; 78(4): 494-502.

Hofmeister CC, Quinn A, Cooke KR, Stiff P, Nickoloff BJ, Ferrara JLM: Graft versus host disease of the skin: life and death on the epidermal edge. Biol Blood Marrow Transpl 10: 366-372, 2004.

Nickoloff BJ, Lingen MW, Chang B-D, Shen M, Swift M, Curry JL, Bacon P, Bodner B, Roninson IB: Tumor suppressor maspin is upregulated during keratinocyte senescence, exerting a paracrine anti-angiogeneic activity. Cancer Res 64: 2956-2961, 2004.

Baldi A, De Falco M, De Luca L, Cotton G, Paggi MG, Nickoloff BJ, Miele L, De Luca A: Characterization of tissue specific expression of Notch-1 in human tissues. Biol of Cell 96: 303-311, 2004.

Nickoloff BJ. The skin cancer paradox of psoriasis: a matter of life and death decisions in the epidermis. Arch Dermatol: 140: 873-875, 2004.

Nickoloff BJ, Nestle FO: Science and Medicine Series: Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities. J Clin Invest 113: 1664-1675, 2004.

Qin J-Z, Stennett L, Bacon P, Bodner B, Hendrix MJ, Seftor RE, Seftor EA, Margaryan NV, Pollock PM, Curtis A, Trent JM, Bennett F, Miele L, Nickoloff BJ. p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas. Mol Cancer Ther 3(8): 895-902, 2004.

Stennett LS, Riker AI, Kroll TM, Chamberlin J, Miki T, Nickoloff BJ, Le Poole C: Expression of GP100 and CDK2 in melanoma cells is not co-regulated by a shared promoter region. Pigment Cell Res 17(5): 525-32, 2004.

Chaturvedi V, Bacon P, Bodner B, Nickoloff BJ. Proliferating cultured human keratinocytes are more susceptible to apoptosis compared with mouse keratinocytes. J Invest Dermatol 123(6): 1200-3, 2004.

Jang MS, Miao H, Carlesso N, Shelly L, Zlobin A, Darack N, Qin JZ, Nickoloff BJ, Miele L. Notch-1 regulates cell death independently of differentiation in murine erythroleukemia cells through multiple apoptosis and cell cycle pathways. J Cell Physiol 199(3): 418-33, 2004.

Sano S, Chan KS, Carbajal S, Clifford J, Peavy M, Kiguchi K, Itami S, Nickoloff BJ, DiGiovanni J. Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model. Nat Med 11(1): 43-49, 2005.

Nickoloff BJ, Bonish BK, Nestle FO. Viewpoint 2. Exp Dermatol 14(1): 72-4, 2005.

Paus R, Nickoloff BJ, Ito T. A ‘hairy’ privilege. Trends Immunol 26(1): 32-40, 2005.

Nestle FO, Nickoloff BJ. From classical mouse models of psoriasis to a spontaneous xenograft model featuring use of AGR mice. Ernst Schering Res Found Workshop (50): 203-12, 2005.

Bacon P, Bodner B, Nickoloff BJ: Senescent human keratinocytes suppress colony formation of HeLa cells. J Dermatol Science 38(1): 64-6, 2005.

Kroll T, Bommiasamy H, Boissy R, Nickoloff BJ, Mestril R, Le Poole IC. Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell mediated killing: relevance to vitiligo. J Invest Dermatol 124(4): 798-806, 2005.

Boyman O, Conrad C, Dudli C, Kielhorn E, Nickoloff BJ, Nestle FO. Activation and expansion of dendritic antigen-presenting cells expressing common heat shock protein receptor CD91 during induction of psoriatic lesions. Brit J Dermatol 152(6): 1211-1218, 2005.

Quinn AM, Brown K, Curry J, Gordon KB, Sinacore J, Gamelli R, Nickoloff BJ. Uncovering histological criteria with prognostic significance in toxic epidermal necrolysis. Arch Dermatol 141(6): 683-687, 2005.

Ben-Neriah Y, Pikarsky E, Nickoloff BJ: Inflammation and Cancer: Is the link as simple as we think? J Invest Dermatol 124(6): x-xiv, 2005.

Chaturvedi V, Sitailo LA, Qin, JZ, Bodner B, Denning MF, Curry J, Zhang W, Brash D, Nickoloff BJ: Knock-down of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-xL reduction thereby enhancing UV-light induced apoptosis. Oncogene, 24(34): 5299-5312, 2005.

Qin JZ, Ziffra J, Stennett L, Bodner B, Bonish BK, Chaturvedi V, Bennett F, Pollock PM, Trent JM, Hendrix MJ, Rizzo P, Miele L, Nickoloff BJ: Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells. Cancer Research, 65(14): 6282-6293, 2005.

Curry CL, Reed LL, Golde TE, Miele L, Nickoloff BJ, Foreman KE: Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi’s sarcoma tumor cells. Oncogene, 24(42):6333-6344, 2005.

Gordon KB, Bonish BK, Patel T, Leonardi CL, Nickoloff BJ: TNF-alpha inhibitor adalimumab rapidly reverses decreases in epidermal langerhans cell density in psoriatic plaques. Brit J Dermatol 153(5): 945-53, 2005.

Hess AR, Postovit LM, Margaryan NV, Seftor EA, Schneider GB, Seftor RE, Nickoloff BJ, Hendrix MJ: Focal adhesion kinase promotes the aggressive mleanoma phenotype. Cancer Res 65(21):9851-9860, 2005.

Seftor EA, Chin L, Kirschmann DA, Feng B, Protopopov A, Brown K, Balagurunathan Y, Trent JM, Nickoloff BJ, Seftor RE, Hendrix MJ: Epigenetic transdifferentiation of normal melanocytes by a metastatic melanoma microenvironment. Cancer Res 65(22): 10164-10169, 2005.

Nickoloff BJ, Hendrix MJ, Pollock PM, Trent JM, Miele L, Qin J-Z: Notch and NOXA Related Pathways in Melanoma Cells. Montagna Symposium Proceedings – J Invest Dermatol Symposium Proceedings 10(2): 95-104, 2005.

Ito T, Ito N, Saathoff M, Stampachiacchiere B, Bettermann A, Takigawa M, Nickoloff BJ, Paus R: Immunology of the human nail apparatus: the infantile nail matrix is a site of relative immune privilege. J Invest Dermatol, 125(6): 1139-1148, 2005.

Bedogni B, Welford SM, Cassarino DS, Nickoloff BJ, Giaccia AJ, Powell MB: The hypoxic microenvironment of the skin contributes to Akt mediated melanocyte transformation. Cancer Cell, 8(6): 443-454, 2005.

Chaturvedi V, Sitailo LA, Bodner B, Denning MF, Nickoloff BJ: Defining the caspase containing apoptotic machinery contributing to cornification in human epidermal equivalents. Exp Dermatol, 15(1): 14-22, 2006.

Chaturvedi V, Bodner B, Qin J-Z, Nickoloff BJ: Knock down of p53 levels in human keratinocytes increases susceptibility to type I and type II interferon-induced apoptosis mediated by a TRAIL dependent pathway. J Dermatol Science, 41(1): 31-41, 2006.

D’Costa AM, Robinson JK, Maududi T, Chaturvedi V, Nickoloff BJ, Denning MF: The proapoptotic tumor suppressor protein kinase C is lost in human squamous cell carcinomas. Oncogene, 25(3): 378-386, 2006.

Perera RJ, Koo S, Bennett CF, Dean NM, Gupta N, Qin JZ, Nickoloff BJ: Defining the transcriptome of accelerated and replicatively senescent keratinocytes reveals links to differentiation, interferon signaling, and Notch related pathways. J Cell Biochem, 98(2): 394-408, 2006.

Nickoloff BJ: Keratinocytes regain momentum as instigators of cutaneous inflammation. Trends Mol Med, 12(3): 102-106, 2006.

Nickoloff BJ, Stevens SR: What have we learned in dermatology from the biologic therapies? J Am Acad Dermatol, 54(3 Suppl 2): S143-S151, 2006.

Wang E, Voiculescu S, LePoole IC, El-Gamil M, Li X, Robbins PF, Nickoloff BJ, Marincola FM. Clonal persistence and evolution during a decade of recurrent melanoma. J Invest Dermatol, 126(6): 1372-1377, 2006.

Miele L, Miao H, Nickoloff BJ: Notch signaling as a novel cancer therapeutic target. Current Cancer Drug Targets, 6(4): 313-323, 2006.

Curry CL, Reed LL, Nickoloff BJ, Miele L, Foreman KE: Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells. Lab Invest, 86(8): 842-852, 2006.

Topczewska JM, Postovit LM, Margaryan NV, Sam A, Hess AR, Wheaton WW, Nickoloff BJ, Topczewski J, Hendrix MJ. Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness. Nat Med, 12(8): 925-32, 2006.

Nestle FO, Nickoloff BJ. Animal models of psoriasis: a brief update. J Eur Acad Dermatol Venereol, 20(Suppl 2): 24-27, 2006.

Leotela PD, Wade MS, Duray PH, Rhode MJ, Brown HF, Rosenthal DT, Dissanayake SK, Earley R, Indig FE, Nickoloff BJ, Taub DD, Kallioniemi OP, Meltzer P, Morin PJ, Weeraratna AT. Claudin-1 overexpression in melanoma is regulated by PKAC and contributes to melanoma cell motility. Oncogene, 26: 3846-3856, 2006.

Nickoloff BJ, Bonish BK, Marble DJ, Schriedel KA, DiPietro LA, Gordon KB, Lingen WV. Lessons learned from psoriatic plaques concerning mechanisms of tissue repair, remodeling and inflammation. J Investig Dermatol Symp Proc, 11(1): 16-29, 2006.

Qin JZ, Xin H, Sitailo LA, Denning MF, Nickoloff BJ. Enhanced killing of melanoma cells by simultaneously targeting MCl-1 and NOXA. Cancer Res.1, 66(19): 9636-9645, 2006.

Nickoloff BJ, Bonish BK, Marble DJ, Schriedel KA, Dipietro LA, Gordon KB, Lingen, MW. Lessons learned from psoriatic plaques concerning mechanisms of tissue repair, remodeling and inflammation. J Invest Dermatol, 126 Suppl: 16-29, 2006.

Govindarajan B, Sligh JE, Vincent BJ, Li M, Canter JA, Nickoloff BJ, Rodenburg RJ, Smeitink JA, Oberley L, Zhang Y, Slingerland J, Arnold RS, Lambeth JD, Cohen C, Hilenski L, Griendling K, Martinez-Diez M, Cuezva JM, Arbiser JL. Overexpression of Akt converts radial growth melanoma to vertical growth melanoma. J Clin Invest, 117(3): 719-29, 2007

Curry, J, Goulder S, Nickoloff BJ. Occurrence of a basal cell carcinoma and dermatofibroma in a smallpox vaccination scar. Derm Surg, 34(1): 132-2, 2007.

Nickoloff BJ. Cracking the cytokine code in psoriasis. Nat Med, 13(3): 242-244, 2007.

Dissanayake SK, Wade, MS, Johnson CE, O’Connell MP, Leotlela PD, French AD, Shah KV, Hewitt KJ, Rosenthal DT, Indig FE, Jiang Y, Nickoloff BJ, Taub DD, Trent JM, Moon RT, Bittner M, Weeraratna AT. The WNT5A/ PKC pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors, and initiation of an epithelial to mesenchymal transition. J Biol Chem, 282(23):17259-71, 2007.

Toor AA, Stiff PJ, Nickoloff BJ, Rodriguez T, Klein JL, Gordon KB. Alefacept in corticosteroid refractory graft versus host disease: early results indicate promising activity. J Dermatolog Treat, 18(1): 13-8, 2007.

Nestle FO, Nickoloff BJ. Deepening our understanding of immune sentinels in the skin. J Clin Invest, 117(9): 2382-2385, 2007.

Marble DJ, Gordon KB, Nickoloff BJ. Targeting TNF rapidly reduces density of dendritic cells and macrophages in psoriatic plaques with restoration of epidermal keratinocyte differentiation. J Derm Sci, 48(2): 87-101, 2007.

Nickoloff BJ, Qin JZ, Nestle FO. Immunopathogenesis of psoriasis. Clin Rev Allergy Immunol, 33(1-2): 45-56, 2007.

Ito T, Ito N, Saatoff M, Hashizume H, Fukamizu H, Nickoloff BJ, Takigawa M, Paus R. Maintenance of hair follicle immune privilege is linked to prevention of NK cell attack. J Invest Dermatol, 128(5):1196-206, 2008.

Sabatino M, Zhao Y, Voiculescu S, Monaco A, Robbins P, Karai L, Nickoloff BJ, Maio M, Selleri S, Marincola FM, Wang E. Conservation of genetic alterations in recurrent melanoma supports the melanoma stem cell hypothesis. Cancer Res, 68(1): 122-31, 2008.

Abood GJ, Nickoloff BJ, Gamelli RL. Treatment strategies in toxic epidermal necrolysis syndrome: Where are we at? J Burn Care Res, 29(1): 269-276, 2008.

Einspahr JG, Timothy Bowden G, Alberts DS, McKenzie N, Saboda K, Warneke J, Salasche S, Ranger-Moore J, Curiel-Lewandrowski C, Nagle RB, Nickoloff BJ, Brooks C, Dong Z, Stratton SP. Cross-validation of Murine UV Signal Transduction Pathways in Human Skin. Photochem Photobiol, Photochem Photobiol., 84(2):463-76, 2008.

Gresik CM, Brewster LP, Abood G, Supple KG, Silver GM, Gamelli RL, Nickoloff, BJ. Ecthyma gangrenosum following toxic epidermal necrolysis syndrom in a 3-year-old boy-a survivable series of events. J Burn Care Res, 29(3):555-8, 2008.

Nickoloff BJ. Immunobiology of acute cytotoxic drug reactions. Curr Dir Autoimmun, 10:53-64, 2008.

Cooper KD, Sontheimer RD, Dutz J, Hwang ST, Nickoloff BJ, Shimada S, Kulesz-Martin M, Bickenbach JR. 56th annual Montagna Symposium on the Biology of Skin: Epidermal T-cell interactions--clinicopathological and basic mechanisms. J Invest Dermatol, 128(6):1351-3, Jun 2008.

Song LL, Peng Y, Yun J, Rizzo P, Chaturvedi V, Weijzen S, Kast WM, Stone PJ, Santos L, Loredo A, Lendahl U, Sonenshein G, Osborne B, Qin JZ, Pannuti A, Nickoloff BJ, Miele L. Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells. Oncogene, 27(44):5833-44, October, 2008.

Rizzo P, Miao H, D'Souza G, Osipo C, Yun J, Zhao H, Mascarenhas J, Wyatt D, Antico G, Hao L, Yao K, Rajan P, Hicks C, Siziopikou K, Selvaggi S, Bashir A, Bhandari D, Marchese A, Lendahl U, Qin JZ, Tonetti DA, Albain K, Nickoloff BJ, Miele L. Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. Cancer Res, 68(13):5226-35, Jul 2008.

Bedogni B, Warneke JA, Nickoloff BJ, Giaccia, AJ, Broome Powell M. Notch1 is an effector of Akt and hypoxia in melanoma development. J Clin Invest, 118(11):3660–3670, November 2008.

Yang G, Li Y, Nishimura EK, Xin H, Zhou A, Guo Y, Dong L, Denning MF, Nickoloff BJ, Cui R. Inhibition of PAX3 by TGF-beta modulates melanocyte viability. Mol Cell, 32(4):554-63, Novemvber 2008.

Nickoloff BJ. Saving the skin from drug-induced detachment. Nat Med, 14(12); 1311-3, December 2008.