Olivia Castellanos (sitting), 31, a resident of Berwyn, Ill., and her husband, Bernardo Hernandez (left), 31, hold two of their quintuplets,Vanessa Guadalupe, Jenette, Christian, Bernardo and Melissa, born at Loyola University Medical Center in Maywood, Ill., on Thursday, Janaury 15. Neonatal intensive care nurses, Soila Valasco (back left) and Linda Rodriguez (front right), and respiratory therapist Halina Fishman (center), watch over three of the babies. Loyola last delivered quintuplets in 1977. Photo by O. Izquierdo/Loyola University Health System. (Used by the Chicago Tribune, Associated Press (AP), Chicago Sun-Times, among others.)

Dr. Richard L. Gamelli, principal investigator; in the PolyHeme blood substitute clinical trial; chairman, Department of Surgery, Loyola University Health System; chief, Burn Center, Loyola University Medical Center; and professor of trauma surgery, Loyola University Chicago Stritch School of Medicine, Maywood, Ill., holds a unit of the blood substitute, which carries oxygen compared to saline (saltwater), the current standard of care for trauma patients who have lost blood due to a traumatic event. In the clinical trial, paramedics will use the blood substitute at the scene of injury to help replace oxygen, a vital nutrient in blood. Ambulances do not carry blood because it has to be refrigerated, expires after 42 days and needs to be cross-matched to the patient’s specific blood type, compared to the new blood substitute, which lasts up to a year and can be used on any patient regardless of his or her blood type. The blood substitute is manufactured by Northfield Laboratories, Evanston, Ill. Photo by O. Izquierdo/Loyola University Health System. (Used by the Daily Southtown, Associated Press (AP), Miami Herald, CBS News, MSNBC, among others.)